Degradation of insensitive munition ingredient 2,4-dinitroanisole by bacteria — ASN Events
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Degradation of insensitive munition ingredient 2,4-dinitroanisole by bacteria (#113)

Gunjan Pandey 1 , Tekle Tafese Fida 2 , Shannu Palamuru 1 , Jim C Spain 1 2
  1. CSIRO, ACTON, ACT, Australia
  2. Department of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA

2,4-Dinitroanisole (DNAN) is an insensitive munition ingredient used in explosive formulations as a replacement for 2,4,6-trinitrotoluene (TNT). Little is known about the environmental fate of DNAN. We have recently isolated a Nocardioides sp. strain JS1661 which has an ability to grow on DNAN as a sole source of carbon and energy. Identification of the genes encoding the key enzymes suggested recent evolution of the pathway by recruitment of a novel hydrolase to extend the well-characterized 2,4-DNP pathway. Potential of JS1661 and its novel hydrolase for waste treatment and explosive degradation is also discussed. 

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